2023
- Proteomic analysis of brain metastatic lung adenocarcinoma reveals intertumoral heterogeneity and specific alterations associated with the timing of brain metastases
Woldmar N., , Schwendenwein A., Kuras M. , Szeitz B. , Boettiger K. , Tisza A., László V- , Reiniger L. , Bagó A. G., Szállási Z. Moldvay J., Szász A. M. Malm J. , Horvatovich P., Pizzatti L. , Domont G. B., Rényi-Vámos F., Hoetzenecker F. , Hoda M. A. , Marko-Varga G., Schelch K. , Megyesfalvi Z., Rezeli M., B. Döme B., ESMO Open, 2023, 8, (1), 1-13
Impact Factor: 4.43
2022
- Prediction of early-stage melanoma recurrence using clinical and histopathologic features.
Wan G., Nga Nguyen N., Feng Liu F., DeSimone M.S., Leung B. W., Rajeh A. ,Collier M. R., , Choi M. S. , Amadife M. , Tang K. , Zhang S. , Phillipps J. S. , Jairath R. , Alexander N. A. , Hua Y., Jiao M , Chen W., Ho1 D. , Stacey Duey1 , Németh I. B. , Marko-Varga G. , Gil Valdés J. , Liu D. ,. Boland G. M. , Gusev A. , Sorger P.L. , Yu K-H., and Semenov Y. R., “”, NPJ Prec. Oncol., 2022, 6, 1-16
Impact Factor: 10.092 - In-depth proteomic analysis reveals unique subtype-specific signatures in human small cell lung cancer.
Szeitz B, Megyesfalvi Z., Woldmar N., Valkó Z., Schwendenwein A. , Bárány N., Paku S. , László V., Bugyik E., Lang C. , Szász A. M. , Pizzatti L. , Hoda M. A., Hoetzenecker K. , Marko-Varga G. , Horvatovich P. , Döme B., Schelch K., Rezeli M.”, Clin. Transl. Sci , 2022, 12, (9), e1060
Impact Factor: 12.53 - Lipid metabolic reprogramming in operable pancreatic cancer and tumor margin
Pirhonen J., Szkalisity A., Hagström J., Kim Y., Migh E., Kovacs M., Hölttä M., Peränen J., Seppänen H., Haglund C., Gil J., Rezeli M., Malm J., Horvath P., Marko-Varga G., Puolakkainen P., Ikonen E., , Cancer Res, 2022, Nov 2;82(21):3932-3949
Impact Factor: 14.099 - Expression patterns and prognostic relevance of subtype-specific transcription factors in surgically resected small cell lung cancer: an international multicenter study
Megyesfalvi Z., Barany N., Lantos A., Valko Z., Pipek O., Lang C., Schwendenwein A., Oberndorfer F., Paku S., Ferencz B., Fillinger J., Lohinai Z., Moldvay J., Galffy G., Rezeli M., Rivard C., Hirsch F. R., Brcic L., Popper H., Kern I., Kovacevic M., Skarda J., Mitták M., Marko-Varga G, Bogos K, Renyi-Vamos F., Hoda A. M., Klikovits T., Hoetzenecker K., Schelch K., Laszlo V., Dome B., J. Pathology, 2022, Aug;257(5):674-686
Impact Factor: 7.99 - Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization
Governa, Talbot, Gonçalves de Oliveira K, Cerezo Magaña, Bång Rudenstam, Johansson, Månsson, Forsberg Nilsson K, Marko Varga G, Enríquez Pérez J, Darabi A, Malmström J Bengzon J, Welinder C, Belting M., PNAS , 2022, 119 (9) e2114456119
Impact Factor: 11.205 - The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition.
Hegedüs L., Livingstone E. Bánkfalvi A., Viehof J., Enyedi A., Bilecz A., Győrffy B., Baranyi M., Tőkés A-M, Gil J., Marko‐varga, G., Griewank K. G., Zimmer L., Váraljai R., Sucker A., Dirk Schadendorf Z. A., Aigner C. and Hegedüs B., 2022, In: Int. J. Mol. Sci., 2022, 23, 6, 3324
2021
- An observational study on the molecular profiling of primary melanomas reveals a progression dependence on mitochondrial activation
Gil, J., Rezeli, M., Lutz, E. G., Kim, Y., Sugihara, Y., Malm, J., Semenov, Y. R., Yu, K. H., Nguyen, N., Wan, G., Kemény, L. V., Kárpáti, S., Németh, I.B. & Marko‐varga, G., 2021 Dec., In: Cancers. 13 , 23, 6066. - Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis
Berta, J., Török, S., Tárnoki-Zách, J., Drozdovszky, O., Tóvári, J., Paku, S., Kovács, I., Czirók, A., Masri, B., Megyesfalvi, Z., Oskolás, H., Malm, J., Ingvar, C., Markó-Varga, G., Döme, B. & László, V., 2021, In: Scientific Reports. 11, 1, 5798. - Deep proteomic analysis on biobanked paraffine-archived melanoma with prognostic/predictive biomarker read-out
Szadai, L., Velasquez, E., Szeitz, B., de Almeida, N. P., Domont, G., Betancourt, L. H., Gil, J., Marko-Varga, M., Oskolas, H., Jánosi, Á. J., Boyano-Adánez, M. D.C., Kemény, L., Baldetorp, B., Malm, J., Horvatovich, P., Szász, A.M., Németh, I.B. & Marko-Varga, G., 2021 Dec., In: Cancers. 13, 23, 6105. - Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact
Cho, S.M., Kim, Y., Jung, Y., Ko, M., Marko-Varga, G. & Kwon, H. J., 2021 Nov., In: Journal of Medicinal Chemistry. 64, 21, p. 15858-15867 10 p. - Mapping the melanoma plasma proteome (MPP) using single-shot proteomics interfaced with the WiMT database
Almeida, N., Rodriguez, J., Parada, I. P., Perez-Riverol, Y., Woldmar, N., Kim, Y., Oskolas, H., Betancourt, L., Valdés, J. G., Sahlin, K.B., Pizzatti, L., Szasz, A.M., Kárpáti, S., Appelqvist, R., Malm, J., Domont, G.B., Nogueira, F.C. S., Marko-Varga, G. & Sanchez, A., 2021 Dec. 1, In: Cancers. 13, 24, 6224. - Organ specific copy number variations in visceral metastases of human melanoma
Papp, O., Doma, V., Gil, J., Markó-Varga, G., Kárpáti, S., Tímár, J. & Vízkeleti, L., 2021 Dec., In: Cancers. 13, 23, 5984. - Pipelines and Systems for Threshold-Avoiding Quantification of LC-MS/MS Data
Sánchez Brotons, A., Eriksson, J. O., Kwiatkowski, M., Wolters, J.C., Kema, I. P., Barcaru, A., Kuipers, F., Bakker, S. J. L., Bischoff, R., Suits, F. & Horvatovich, P., 2021 Aug. 17, In: Analytical Chemistry. 93, 32, p. 11215-11224 10 p. - Proteomic Workflows for High-Quality Quantitative Proteome and Post-Translational Modification Analysis of Clinically Relevant Samples from Formalin-Fixed Paraffin-Embedded Archives
Kuras, M., Woldmar, N., Kim, Y., Hefner, M., Malm, J., Moldvay, J., Dome, B., Fillinger, J., Pizzatti, L., Gil, J., Marko-Varga, G. & Rezeli, M., 2021, In: Journal of Proteome Research. 20, 1, pp. 1027–1039 - The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome
Betancourt, L. H., Gil, J., Sanchez, A., Kuras, M., Velasquez, E., Kim, Y., Sugihara, Y., Parada, I. P., Appelqvist, R., Wieslander, E., Welinder, C., de Almeida, N. P., Woldmar, N., Marko-Varga, M., Eriksson, J., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Lindberg, H.& 15 others, , 2021, In: Clinical and Translational Medicine. 11, 7, pp. 1-25 e451. - The human melanoma proteome atlas-Defining the molecular pathology
Betancourt, L. H., Gil, J., Kim, Y., Doma, V., Çakır, U., Sanchez, A., Murillo, J. R., Kuras, M., Parada, I. P., Sugihara, Y., Appelqvist, R., Wieslander, E., Welinder, C., Velasquez, E., de Almeida, N. P., Woldmar, N. , Marko-Varga, M., Pawłowski, K., Eriksson, J., Szeitz, B. & 37 others, , 2021, In: Clinical and Translational Medicine. 11, 7, pp. 1-20 e473.
2020
- MSIWarp: A General Approach to Mass Alignment in Mass Spectrometry Imaging
Eriksson, J. O., Sánchez Brotons, A., Rezeli, M., Suits, F., Markó-Varga, G. & Horvatovich, P., 2020, In: Analytical Chemistry. 92, 24, pp. 16138–16148 - Novel functional proteins coded by the human genome discovered in metastases of melanoma patients
Sanchez, A., Kuras, M., Murillo, J. R., Pla, I., Pawlowski, K., Szasz, A.M., Gil, J., Nogueira, F.C. S., Perez-Riverol, Y., Eriksson, J., Appelqvist, R., Miliotis, T., Kim, Y., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Ekedahl, H., Horvatovich, P., Sugihara, Y.& 8 others, , 2020 June, In: Cell Biology and Toxicology. 36, 3, p. 261-272 12 p. - Protein Expression in Metastatic Melanoma and the Link to Disease Presentation in a Range of Tumor Phenotypes
Kim, Y., Gil, J., Pla, I., Sanchez, A., Betancourt, L. H., Lee, B., Appelqvist, R., Ingvar, C., Lundgren, L., Olsson, H., Baldetorp, B., Kwon, H. J., Oskolás, H., Rezeli, M., Doma, V., Kárpáti, S. , Szasz, A.M., Németh, I.B., Malm, J. & Marko-Varga, G., 2020 Mar 24, In: Cancers. 12, 3, 767. - A biobanking turning-point in the use of formalin-fixed, paraffin tumor blocks to unveil kinase signaling in melanoma
A biobanking turning-point in the use of formalin-fixed, paraffin tumor blocks to unveil kinase signaling in melanoma
Velasquez, E., Szadai, L., Zhou, Q., Kim, Y., Pla, I., Sanchez, A., Appelqvist, R., Oskolas, H., Marko-Varga, M., Lee, B., Kwon, H. J., Malm, J., Szász, A.M., Gil, J., Betancourt, L. H., Németh, I.B. & Marko-Varga, G., 2021, In: Clinical and Translational Medicine. 11, 8, p. 1-6 e466. - Matrix-assisted laser desorption ionization – mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non-small-cell lung cancer mouse xenograft model
Kim, T. Y., Lee, B., Kim, Y., Sugihara, Y., Rezeli, M., Szasz, A.M., Dome, B., Marko-Varga, G. & Kwon, H. J., 2021, In: Clinical and Translational Medicine. 11, 7, e481. - Targeting the hydrophilic regions of recombinant proteins by MS via in-solution buffer-free trypsin digestion
Betancourt, L. H., Espinosa, L. A., Ramos, Y., Bequet-Romero, M., Rodríguez, E. N., Sánchez, A., Marko-Varga, G., González, L. J. & Besada, V., 2020 Jun 1, In: European Journal of Mass Spectrometry. 26, 3, p. 230-237 8 p.
2019
- Assessing Automated Sample Preparation Technologies for High-Throughput Proteomics of Frozen Well Characterized Tissues from Swedish Biobanks
Kuras, M., Betancourt, L. H., Rezeli, M., Rodriguez, J., Szasz, M., Zhou, Q., Miliotis, T., Andersson, R. & Marko-Varga, G., 2019, In: Journal of Proteome Research. 18, 1, pp. 548–556 9 p. - Challenging the heterogeneity of disease presentation in malignant melanoma—impact on patient treatment
Marcell Szasz, A., Malm, J., Rezeli, M., Sugihara, Y., Betancourt, L. H., Rivas, D., Gyorffy, B. & Marko-Varga, G., 2019, In: Cell Biology and Toxicology. 35, 1, p. 1-14 - Clinical protein science in translational medicine targeting malignant melanoma
Gil, J., Betancourt, L. H., Pla, I., Sanchez, A., Appelqvist, R., Miliotis, T., Kuras, M., Oskolas, H., Kim, Y., Horvath, Z., Eriksson, J., Berge, E., Burestedt, E., Jönsson, G., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Horvatovich, P., Murillo, J. R. & 18 others, , 2019, In: Cell Biology and Toxicology. 35, 4, p. 293-332 - Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data
Betancourt, L. H., Pawłowski, K., Eriksson, J., Szasz, A.M., Mitra, S., Pla, I., Welinder, C., Ekedahl, H., Broberg, P., Appelqvist, R., Yakovleva, M., Sugihara, Y., Miharada, K., Ingvar, C., Lundgren, L., Baldetorp, B., Olsson, H., Rezeli, M., Wieslander, E., Horvatovich, P. & 3 others, , 2019 March 26, In: Scientific Reports. 9, 1, 5154. - The hidden story of heterogeneous B-raf V600E mutation quantitative protein expression in metastatic melanoma—association with clinical outcome and tumor phenotypes
Betancourt, L. H., Szasz, A. M., Kuras, M., Murillo, J. R., Sugihara, Y., Pla, I., Horvath, Z., Pawłowski, K., Rezeli, M., Miharada, K., Gil, J., Eriksson, J., Appelqvist, R., Miliotis, T., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Horvatovich, P., Welinder, C. & 8 andra, , 2019, I: Cancers. 11, 12, 1981.
2018
- Automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue
Murillo, J. R., Kuras, M., Rezeli, M., Milliotis, T., Betancourt, L. & Marko-Varga, G., 2018 dec. 10, I: PLoS ONE. 13, 12, e0208562. - Endogenous expression mapping of malignant melanoma by mass spectrometry imaging
Sugihara, Y., Rivas, D., Malm, J., Szasz, M., Kwon, H., Baldetorp, B., Olsson, H., Ingvar, C., Rezeli, M., Fehniger, T. E. & Marko-Varga, G., 2018 aug. 6, I: Clinical and Translational Medicine. 7, s. 1-9 22. - Quantitative Assessment of Urea In-Solution Lys-C/Trypsin Digestions Reveals Superior Performance at Room Temperature over Traditional Proteolysis at 37 °C.
Betancourt, L., Sanchez, A., Pla Parada, I., Kuras, M., Zhou, Q., Andersson, R. & Marko-Varga, G., 2018 maj 29, I: Journal of Proteome Research. 17, 7, s. 2556−2561 6 s.